dinsdag 18 februari 2014

Detailed Y chromosome DNA sequencing data.

In 2013, a major part of the Recourt Y chromosome has been sequenced by the US company Full Genome Corporation (ref.1). This analysis revealed 59 additional DNA mutations, from which a number may be shared by DNA cousins. If so, these 'private' mutations will be earmarked as SNPs (Single Nucleotide Polymorphisms), characterizing subhaplogroups downstream of Z36. The physical location of SNP Z36 which is about 4000 years old, can be found at the most recent ISOGG YDNA SNP index map (ref.2 & 7).  The position of additional downstream Recourt mutations at the Y chromosome, their characteristics and the respective names are summarized hereafter.


 
 

 
The physical locations of the DNA mutations at the Y chromosome are statistically shown hereafter.







 

More and more Z36 individuals are tested for their Y chromosome DNA sequences and recently it has been shown that SNP FGC6511+ is also found in another R-Z36 individual (see blog article Dec. 2014).

Please also review recent developments at the Anthrogenica forum and the developing R-Z36 tree at the Yfull community and especially at the FT DNA U152 page (refs 5 & 8). The ID of the Recourt Y chromosome is YF01743 and FGC-LXS7L. The DNA Phylogeny is more and more based on Y chromosomal DNA sequence data.



References

(1) https://www.fullgenomes.com/

(2) http://www.isogg.org/tree/ISOGG_YDNA_SNP_Index.html

(3) SNP mutation rate of approx. 1 - 2.5 * 10(-8) Mbp per generation.
or 4 * 10-8 per nucleotide per generation equals 1 SNP per 25 Mbp per generation.

(4) Fluxus Engineering (website).

(5) Family Tree DNA R-U152 and Subclades Research Project (Results page).

(6) List of STR markers, Wikipedia.

(7) Both Fluxus -and STR variance analysis suggest that the age of Z36 is about 4000-4500 yrs. This may mean that each recorded Y DNA mutation (55) represents about 70-80 yrs. The latter period may correspond with one novel point mutation per 3 generations. (1 generation about 25 years).

(8) http://www.yfull.com